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مقاله Development of mechanical stress in a moving cell : a continuum model تحت pdf دارای 9 صفحه می باشد و دارای تنظیمات در microsoft word می باشد و آماده پرینت یا چاپ است

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بخشی از متن مقاله Development of mechanical stress in a moving cell : a continuum model تحت pdf :

سال انتشار: 1392
محل انتشار: پانزدهمین کنفرانس دینامیک شاره ها (سیالات)
تعداد صفحات: 9
چکیده:

There is a network of protein filaments in the front part of a motile cell, which is called actin network. The actin filaments (F-actins) are constantly polymerizing and elongating at the leading edge of the cell. Indeed, these filaments want to move forward. However, the cell membrane resists against actins movement and causes actin retrograde flow. Based on the actin flow velocity and structure of actin filaments, the front part of the cell is organized into a lamellipodium and a lamellum. Any moving cell adheres to the extracellular matrix (ECM) via focal adhesions. A certain lamellipodium-lamellum boundary is associated with the focal adhesions and consists of a series of arclike segments linking neighboring focal adhesions. In this work, a simple continuum model from the front part of the cell for lamellipodium-lamellum boundary generation with stress distribution in the actin network is presented. The actin network is assumed as a highly viscous Newtonian fluid. Since, the lamellipodium-lamellum boundary is a critical region for stress, the actin filaments probably are disintegrated on this boundary and the new structure of them will be formed. The critical stress for actin filaments in fluid is also obtained.

 

 

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